CYP1A1 Gene Polymorphism in Korean Women with Endometriosis / 대한산부인과학회지
Korean Journal of Obstetrics and Gynecology
;
: 1484-1489, 2005.
Artículo
en Coreano
| WPRIM
| ID: wpr-14103
ABSTRACT
OBJECTIVE:
To explore the association of the CYP 1A1 gene polymorphism with the risk of endometriosis in a Korean population.DESIGN:
Case-control studyMETHODS:
Two-hundred fifty two Korean women with surgically or histologically diagnosed endometriosis of stage I-IV (ASRM, 1997) were recruited, and 203 women with no evidence of endometriosis served as controls. CYP1A1 gene MspI polymorphism was analyzed by polymerase chain reaction (PCR) and restriction fragment length polymorphism analysis.RESULTS:
There was no significant difference in the genotype or allele distribution of CYP1A1 gene polymorphism between patients with endometriosis and controls. And when classified by stage, there was also no significant difference in the genotype and allele distribution of CYP1A1 gene MspI polymorphism between patients with stage I-II or stage III-IV endometriosis and controls.CONCLUSION:
These results suggest that CYP1A1 gene MspI polymorphism is not associated with the risk of endometriosis in the Korean women.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Polimorfismo de Longitud del Fragmento de Restricción
/
Estudios de Casos y Controles
/
Reacción en Cadena de la Polimerasa
/
Citocromo P-450 CYP1A1
/
Endometriosis
/
Alelos
/
Genotipo
Tipo de estudio:
Estudio observacional
/
Factores de riesgo
Límite:
Femenino
/
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Obstetrics and Gynecology
Año:
2005
Tipo del documento:
Artículo
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