The Molecular Pathogenesis of Pituitary Adenomas: An Update
Endocrinology and Metabolism
;
: 245-254, 2013.
Artículo
en Inglés
| WPRIM
| ID: wpr-141196
ABSTRACT
Pituitary tumors represent the most common intracranial neoplasms accompanying serious morbidity through mass effects and inappropriate secretion of pituitary hormones. Understanding the etiology of pituitary tumorigenesis will facilitate the development of satisfactory treatment for pituitary adenomas. Although the pathogenesis of pituitary adenomas is largely unknown, considerable evidence indicates that the pituitary tumorigenesis is a complex process involving multiple factors, including genetic and epigenetic changes. This review summarized the recent progress in the study of pituitary tumorigenesis, focusing on the role of tumor suppressor genes, oncogenes and microRNAs.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Oncogenes
/
Hormonas Hipofisarias
/
Neoplasias Hipofisarias
/
Neoplasias Encefálicas
/
Ciclo Celular
/
Transformación Celular Neoplásica
/
Genes Supresores de Tumor
/
MicroARNs
/
Epigenómica
Tipo de estudio:
Estudio de etiología
Idioma:
Inglés
Revista:
Endocrinology and Metabolism
Año:
2013
Tipo del documento:
Artículo
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