Radiation Recall Dermatitis Induced by Gefitinib / 이화의대지
The Ewha Medical Journal
; : S17-S21, 2013.
Article
en Ko
| WPRIM
| ID: wpr-141202
Biblioteca responsable:
WPRO
ABSTRACT
Radiation recall dermatitis refers to an acute inflammatory reaction in a previously irradiated field triggered by the administration of certain drugs days to years after the exposure to radiation. Gefitinib is an epidermal growth factor receptor tyrosine kinase inhibitor and is an effective treatment for patients with advanced stage of non small cell lung cancer (NSCLC). Here, we report a rare case of gefitinib induced radiation recall dermatitis. A 52-year-old woman with a metastatic NSCLC had received a palliative radiation therapy of 20 cGy on spine metastasis area (C6-T6). After 24 days of receiving radiation therapy, she had started to take gefitinib. Eight months after taking drug, pain, swelling and erythema of skin were occurred on previously irradiated field. These symptoms were resolved after the cessation of gefitinib for 6 days and the topical use of steroid.
Palabras clave
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Radiodermatitis
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Piel
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Columna Vertebral
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Proteínas Tirosina Quinasas
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Eritema
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Carcinoma Pulmonar de Células Pequeñas
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Receptores ErbB
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Neoplasias Pulmonares
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Metástasis de la Neoplasia
Límite:
Female
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Humans
Idioma:
Ko
Revista:
The Ewha Medical Journal
Año:
2013
Tipo del documento:
Article