Understanding asthma using animal models
Allergy, Asthma & Immunology Research
;
: 10-18, 2009.
Artículo
en Inglés
| WPRIM
| ID: wpr-141245
ABSTRACT
Asthma is a complex syndrome with many clinical phenotypes in children and adults. Despite the rapidly increasing prevalence, clinical investigation and epidemiological studies of asthma, the successful introduction of new drugs has been limited due to the different disease phenotypes and ethical issues. Mouse models of asthma replicate many of the features of human asthma, including airway hyperreactivity, and airway inflammation. Therefore, examination of disease mechanisms in mice has been used to elucidate asthma pathology and to identify and evaluate new therapeutic agents. In this article, we discuss the various animal models of asthma with a focus on mouse strains, allergens, protocols, and outcome measurements.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Fenotipo
/
Asma
/
Alérgenos
/
Prevalencia
/
Modelos Animales
/
Inflamación
Tipo de estudio:
Guía de Práctica Clínica
/
Estudio de prevalencia
Límite:
Animales
/
Humanos
Idioma:
Inglés
Revista:
Allergy, Asthma & Immunology Research
Año:
2009
Tipo del documento:
Artículo
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