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Surgical Experiences of Functioning Neuroendocrine Neoplasm of the Pancreas
Yonsei Medical Journal ; : 833-839, 2006.
Artículo en Inglés | WPRIM | ID: wpr-141746
ABSTRACT
We present our surgical experiences with functioning neuroendocrine neoplasms of the pancreas to define its natural history, and to suggest its proper management. From June 1990 to June 2005, patients with diagnosis of functioning neuroendocrine (islet cell) neoplasms of the pancreas were retrospectively reviewed. Fourteen patients (5 men and 9 women) with a median age of 49 years (range, 12 - 68 years) were identified. Twelve patients (86%) had insulinoma, two (14%) had gastrinoma. One (7%) with pancreatic insulinoma was multiple endocrine neoplasia type 1. Intraoperative ultrasound scan (sensitivity, 83%) was the most powerful modality for tumor localization. Fifteen neoplasms with median tumor size 1 cm (range 0-3 cm) were resected. Four insulinomas (26.7%) were located in the head of the pancreas and 5 (36%), in the tail. Another 5 (36%) insulinomas and 1 (7%) gastrinoma were located around the neck area near the SMV or PV. Eleven patients (79%) underwent enucleation, and 2 patients (14%), distal pancreatectomy with splenectomy. 100% of patients with functioning neuroendocrine neoplasms of the pancreas have survived. The overall disease free 10-year survival was found to be about 81%. Exact localization of tumor by intraoperative ultrasound and surgical removal are promising for good prognosis.
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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Neoplasias Pancreáticas / Complicaciones Posoperatorias / Pronóstico / Gastrinoma / Estudios Retrospectivos / Insulinoma / Metástasis de la Neoplasia Tipo de estudio: Estudio observacional / Estudio pronóstico Límite: Adolescente / Adulto / Anciano / Niño / Femenino / Humanos / Masculino Idioma: Inglés Revista: Yonsei Medical Journal Año: 2006 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Neoplasias Pancreáticas / Complicaciones Posoperatorias / Pronóstico / Gastrinoma / Estudios Retrospectivos / Insulinoma / Metástasis de la Neoplasia Tipo de estudio: Estudio observacional / Estudio pronóstico Límite: Adolescente / Adulto / Anciano / Niño / Femenino / Humanos / Masculino Idioma: Inglés Revista: Yonsei Medical Journal Año: 2006 Tipo del documento: Artículo