Clinicopathologic Characteristics of and Surgical Strategy for Patients with Submucosal Gastric Carcinomas
Journal of the Korean Gastric Cancer Association
;
: 89-94, 2005.
Artículo
en Coreano
| WPRIM
| ID: wpr-141772
ABSTRACT
PURPOSE:
Early gastric cancer (EGC) has an excellent prognosis compared to advanced gastric cancer. The 5-year survival rate for EGC now exceeds 90%, and EGC is recognized as a curable malignancy. The important prognostic factor in EGC is the status of lymph-node metastasis. Despite conserving surgery being suggested for EGC at present, it is of vital importance to select a surgical method appropriate to each individual case. This retrospective study was undertaken to clarify clinicopathologic features and factors related to lymph-node metastasis in submucosal gastric cancer in order to determine an appropriate therapy. MATERIALS ANDMETHODS:
This study analyzed the clinicopathologic features for 279 patients with a submucosal gastric carcinoma (Group I) and compared with those of patients with mucosal (Group II) or muscularis proprial gastric carcinoma (Group III). All patients were operated on from 1981 to 1999 at Chonnam University Hospital. There were no statistically significant differences among the groups with respect to age, gender, tumor location, hepatic metastasis, or peritoneal dissemination.RESULTS:
Positive lymph node metastasis was found in 47 (16.8%) of the 279 patients with a submucosal gastric carcinoma. The incidence of lymph-node metastasis was significantly higher in patients with a submucosal gastric carcinoma than in patients with a mucosal gastric carcinoma (16.8% vs. 3.9%; P<0.01). Therefore, depth of invasion was a significant factor affecting in lymph-node metastasis. The 5-year survival rates were 88.6% for patients in Group I, 95.2% for patients in Group II, and 72.7% for patients in Group III (P<0.01 for Group I vs. Group II; Group I vs. Group III). In patients with a submucosal gastric carcinoma, the survival rate with positive lymph nodes was significantly poorer than that of patients without lymph-node metastasis (87.3% vs. 94.2%; P<0.01).CONCLUSION:
Gastrectomy with D2 lymph node dissection is an appropriate operative procedure for patients with a submucosal gastric carcinoma.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Pronóstico
/
Neoplasias Gástricas
/
Procedimientos Quirúrgicos Operativos
/
Incidencia
/
Tasa de Supervivencia
/
Estudios Retrospectivos
/
Gastrectomía
/
Escisión del Ganglio Linfático
/
Ganglios Linfáticos
/
Metástasis de la Neoplasia
Tipo de estudio:
Estudio de incidencia
/
Estudio observacional
/
Estudio pronóstico
Límite:
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Gastric Cancer Association
Año:
2005
Tipo del documento:
Artículo
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