Functional Magnetic Resonance Imaging with Arterial Spin Labeling: Techniques and Potential Clinical and Research Applications
Investigative Magnetic Resonance Imaging
; : 91-96, 2017.
Article
en En
| WPRIM
| ID: wpr-141825
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WPRO
ABSTRACT
PURPOSE: To describe technical methods for functional magnetic resonance imaging (fMRI) study with arterial spin labeling (ASL) compared to blood oxygenation level-dependent (BOLD) technique and discuss the potential of ASL for research and clinical practice. MATERIALS AND METHODS: Task-based (n = 1) and resting-state fMRI (rs-fMRI) (n = 20) were performed using ASL and BOLD techniques. Results of both techniques were compared. RESULTS: For task-based fMRI with finger-tapping, the primary motor cortex of the contralateral frontal lobe and the ipsilateral cerebellum were activated by both BOLD and ASL fMRI. For rs-fMRI of sensorimotor network, functional connectivity showed similar results between BOLD and ASL. CONCLUSION: ASL technique has potential application in clinical and research fields because all brain perfusion imaging, CBF measurement, and rs-fMRI study can be performed in a single acquisition.
Palabras clave
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Índice:
WPRIM
Asunto principal:
Oxígeno
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Encéfalo
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Imagen por Resonancia Magnética
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Cerebelo
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Imagen de Perfusión
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Lóbulo Frontal
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Corteza Motora
Idioma:
En
Revista:
Investigative Magnetic Resonance Imaging
Año:
2017
Tipo del documento:
Article