Association of acute tubular necrosis with gross hematuria in cirrhosis-related immunoglobulin A nephropathy
Kidney Research and Clinical Practice
;
: 43-46, 2013.
Artículo
en Inglés
| WPRIM
| ID: wpr-142104
ABSTRACT
Immunoglobulin A (IgA) nephropathy associated with cirrhosis is the most common form of secondary IgA nephropathy (IgAN). Cirrhosis-related IgAN is usually clinically silent with a rare occurrence of gross hematuria, unlike in cases of idiopathic IgAN. Especially, acute tubular necrosis (ATN) associated with gross hematuria is very rare in cirrhosis-related IgAN, although acute renal failure is a frequently reported complication in advanced cirrhosis. Herein, we report an unusual case of ATN requiring renal replacement therapy, associated with gross hematuria in a patient with nonalcoholic, hepatitis B virus-associated cirrhosis. Results of a histopathological analysis revealed obstruction of the lumen of renal tubules by red blood cell casts, a marked tubular necrosis, and IgA deposition in the mesangium. The patient's renal function and gross hematuria were clearly improved after lamivudine treatment.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Fibrosis
/
Inmunoglobulina A
/
Inmunoglobulinas
/
Terapia de Reemplazo Renal
/
Lamivudine
/
Eritrocitos
/
Insuficiencia Renal
/
Lesión Renal Aguda
/
Glomerulonefritis por IGA
/
Hematuria
Límite:
Humanos
Idioma:
Inglés
Revista:
Kidney Research and Clinical Practice
Año:
2013
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS