Proliferative Effect of Retinal Glial Cells by Growth Factors
Journal of the Korean Ophthalmological Society
;
: 1179-1187, 1997.
Artículo
en Coreano
| WPRIM
| ID: wpr-14245
ABSTRACT
The authors tried to evaluate the effect of the growth factors on cell proliferation in the human retina astrocyte culture. Each growth factor, EGF, bFGF, GGF, IGF-1 or PDGF, together with BrdU was added to astrocytes-enriched cultures in the serum-free media. The proliferating effect of each growth factor was evaluated by a double immunofluo- rescenece labelling for GFAP and BrdU. By and addition of each growth factor, the number of retinal astrocytes at the synthetic stage significantly increased than those of control group (p<0.01). In comparision, PDGF was more potent than IGF-1 (p<0.01). Above data extended the concept of astrocytic proliferation caused by several growth factors in human retinal injury.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Retina
/
Retinaldehído
/
Bromodesoxiuridina
/
Factor I del Crecimiento Similar a la Insulina
/
Neuroglía
/
Astrocitos
/
Medio de Cultivo Libre de Suero
/
Péptidos y Proteínas de Señalización Intercelular
/
Proliferación Celular
/
Factor de Crecimiento Epidérmico
Límite:
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Ophthalmological Society
Año:
1997
Tipo del documento:
Artículo
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