Overview and Evaluation of Pulmonary Hypertension

ABSTRACT

The Prevalence of pediatric pulmonary hypertension is rare in general population, and the etiology of this disease is diverse or unknown. But, in recent years, remarkable understanding of vascular biology, normal and hypertensive pulmonary circulation has made an effort to the pathophysiology of pulmonary arterial hypertension. These efforts are adapted the patients treatments with new advanced drugs. In this reviw, we discuss the definition and the clinical classification of pulmonary hypertension, current concepts in the pathophysiology, diagnosis, and managements of pulmoanry hypertension. But, Despite of significant development of therapy, the patients with pulmonary hypertension in pediatric division are rare, so multicenter study in clinical setting is necessary to improve the quality of life and survival for them.