Antibiotic Resistance and Treatment Update of Community-Acquired Pneumonia / 대한내과학회지
Korean Journal of Medicine
;
: 690-698, 2011.
Artículo
en Coreano
| WPRIM
| ID: wpr-143847
ABSTRACT
The emergence of penicillin-resistant S. pneumoniae has issued in the management of community-acquired pneumonia (CAP). However, the clinical outcome did not match with penicillin resistance. Thus, recent (Jan/2008) change of penicillin breakpoints for nonmeningeal strain was done and this made prevalence of penicillin resistance under 5% worldwide. Macrolide resistance of S. pneumoniae in Korea is prevalent (70-80%). Thus, the Korean CAP guideline did not include macrolide monotherapy as empiric therapy. Fluoroquinolone resistance of pneumococcus is very low, however, concerning of the increase of resistance is present.Some new antibiotics for the multidrug resistant S. pneumoniae should be reserved for the future. Macrolide resistance of Mycoplasma pneumoniae is reported in various regions in the world, however, data of the clinical significance is rare. Increased beta-lactamase production of Haemophilus influenzae urges us to use beta-lactam/beta-lactamase or 3rd generation cephalosporin if Haemophilus is pathogen. Pneumococcal vaccine usage is an effective way to prevent invasive diseases by S. pneumoniae (including resistant pathogen). The rate of pneumococcal vaccination in Korea is very low (0.8% in adult). Strategies to control resistance that include effective antimicrobial treatment, vaccination, infection control, appropriate policies and regulations, 'antibiotic stewardship' and education of appropriate antibiotic use, are greatly in need.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Penicilinas
/
Neumonía
/
Neumonía por Mycoplasma
/
Control Social Formal
/
Esguinces y Distensiones
/
Streptococcus pneumoniae
/
Beta-Lactamasas
/
Farmacorresistencia Microbiana
/
Resistencia a las Penicilinas
/
Haemophilus
Tipo de estudio:
Guía de Práctica Clínica
/
Estudio de prevalencia
País/Región como asunto:
Asia
Idioma:
Coreano
Revista:
Korean Journal of Medicine
Año:
2011
Tipo del documento:
Artículo
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