Effects of a Novel Push-through Technique Using the Implantable Collamer Lens Injector System for Graft Delivery during Endothelial Keratoplasty
Korean Journal of Ophthalmology
;
: 87-92, 2013.
Artículo
en Inglés
| WPRIM
| ID: wpr-143920
ABSTRACT
PURPOSE:
To investigate effects of a new push-through insertion method for donor lenticules using an injector system on endothelial viability ex vivo and in a clinical case series of endothelial keratoplasty.METHODS:
An ex vivo delivery model was used with porcine corneoscleral rims. We compared the endothelial viability in a new push-through insertion method using the Visian Implantable Collamer Lens (ICL) injector versus that of standard forceps-assisted insertion for lenticule delivery. Twenty porcine corneal lenticules were divided into four groups by insertion method and wound size. Vital dye staining was performed and devitalized areas were semi-quantitatively assessed by digital imaging. In the clinical case series, Descemet's stripping endothelial keratoplasty (DSEK) using the push-through method was performed in seven patients and endothelial outcome was determined six months postoperatively.RESULTS:
Mean devitalized areas for the push-through method were significantly lower than for forceps-assisted insertion through 3.2 mm incision (23.99 +/- 2.17% vs. 50.48 +/- 5.07%, p = 0.009) in the ex vivo model. Average endothelial cell counts of donor tissues of patients who underwent DSEK were 26.4% lower six months postoperatively.CONCLUSIONS:
Push-through delivery of donor lenticules using the Visian ICL injector system appears to be less harmful to endothelial cells than conventional forceps-assisted delivery.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Complicaciones Posoperatorias
/
Diseño de Prótesis
/
Porcinos
/
Implantación de Lentes Intraoculares
/
Modelos Animales
/
Pérdida de Celulas Endoteliales de la Córnea
/
Queratoplastia Endotelial de la Lámina Limitante Posterior
/
Lentes Intraoculares
Límite:
Animales
Idioma:
Inglés
Revista:
Korean Journal of Ophthalmology
Año:
2013
Tipo del documento:
Artículo
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