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A Case of Primary Pulmonary Histiocytosis-X associated With Central diabetes insipidus / 결핵
Tuberculosis and Respiratory Diseases ; : 110-115, 1999.
Artículo en Coreano | WPRIM | ID: wpr-148400
ABSTRACT
Pulmonary histiocytosis X is a granulomatous disorder of the lung of unknown cause. Patients with this disease often complain of cough, dyspnea on exertion and , occaionally, chest pain from pneumothorax or bone involvement. However, DI is uncommon in these patients. We report a case of primary pulmonary histiocytosis X with central diabetes insipidus. A 23-year-old man presented with dyspnea suffered from dry cough, exertional dyspnea, polydipsia and polyuria for 4 months. He was a heavy smoker. He was found to have reticulonodular interstitial opacities on chest X-ray film. High-resolution computed tomography revealed thin-walled cysts of various sizes in both lungs. Open lung biopsy was done. On light microscopic examination revealed proliferation and infiltration of Langerhans cells. Immunohistochemically, Langerhans cells showed strong cytoplasmic staining with S-100 protein and electronmicroscopic examination showed Birbeck granules in Langerhans cells. Water deprivation test showed central-type diabetes insipidus and brain MRI showed no abnormal lesion on suprasellar region. Smoking cessation was recommended. He was treated with oral desmopressin.
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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Neumotórax / Poliuria / Tórax / Privación de Agua / Película para Rayos X / Biopsia / Dolor en el Pecho / Encéfalo / Imagen por Resonancia Magnética / Proteínas S100 Límite: Humanos Idioma: Coreano Revista: Tuberculosis and Respiratory Diseases Año: 1999 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Neumotórax / Poliuria / Tórax / Privación de Agua / Película para Rayos X / Biopsia / Dolor en el Pecho / Encéfalo / Imagen por Resonancia Magnética / Proteínas S100 Límite: Humanos Idioma: Coreano Revista: Tuberculosis and Respiratory Diseases Año: 1999 Tipo del documento: Artículo