A Case of Hypersensitivity Pneumonitis Caused by Methotrexate / 결핵
Tuberculosis and Respiratory Diseases
;
: 203-209, 2004.
Artículo
en Coreano
| WPRIM
| ID: wpr-148835
ABSTRACT
BACKGROUND:
Methotrexate (MTX) has been used to treat a wide range of malignant and benign diseases including osteosarcoma, advanced stage non-Hodgkin's lymphoma, psoriasis, severe rheumatoid arthritis, sarcoidosis, and Wegener's granulomatosis. MTX-induced lung injury occurs in up to 10% of treated patients. Although both acute and chronic presentations have been described, typical manifestation of MTX-induced lung injury is subacute with symptoms usually developing within several months after starting therapy. Nonspecific interstitial pneumonia (NSIP) is the most common histopathologic manifestation of MTX-induced lung disease, while bronchiolitis obliterans organizing pneumonia (BOOP) and diffuse alveolar damage (DAD) are less common. Granuloma formation is reported in 34.7%. In Korea, Two reports of MTX pneumonitis have been published. The one presented with NSIP and the other with DAD. We recently experienced a case of MTX pneumonitis with presentation of hypersensitivity pneumonitis.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Neumonía
/
Artritis Reumatoide
/
Psoriasis
/
Sarcoidosis
/
Linfoma no Hodgkin
/
Osteosarcoma
/
Granulomatosis con Poliangitis
/
Metotrexato
/
Enfermedades Pulmonares Intersticiales
/
Neumonía en Organización Criptogénica
Límite:
Humanos
País/Región como asunto:
Asia
Idioma:
Coreano
Revista:
Tuberculosis and Respiratory Diseases
Año:
2004
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS