The Effect of Pomegranate on Depression, Anxiety, and Food Intake in Ovariectomized Rats / 대한폐경학회지
The Journal of Korean Society of Menopause
;
: 39-45, 2010.
Artículo
en Coreano
| WPRIM
| ID: wpr-152928
ABSTRACT
OBJECTIVES:
To determine whether or not pomegranate extract can affect depression, anxiety, and food intake in ovariectomized rats.METHODS:
Seventy-nine female Sprague-Dawley rats were divided into six groups A, no operation and no drug intake; B, sham operation and distilled water; C, ovariectomy and distilled water; D, ovariectomy and 10% dilute pomegranate extract; E, ovariectomy and 20% dilute pomegranate extract; and F, ovariectomy and 40% dilute pomegranate extract. Beginning 2 days after surgery, drugs were administrated for 4 weeks. After that, the rats were subjected to the elevated plus maze (EPM) test and forced swim test (FST).RESULTS:
The 10% pomegranate extract had a lower % closed arm entry frequency in the EPM test. A pomegranate dose-dependent decrease in the duration of immobility duration in FST was shown. Pomegranate did not reverse ovariectomy-related hyperphagia and weight gain.CONCLUSION:
Pomegranate extract improved depression and anxiety in a postmenopausal model with ovariectomized rats.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Ansiedad
/
Brazo
/
Ovariectomía
/
Hiperfagia
/
Salicilamidas
/
Ratas Sprague-Dawley
/
Lythraceae
/
Depresión
/
Ingestión de Alimentos
Límite:
Animales
/
Femenino
/
Humanos
Idioma:
Coreano
Revista:
The Journal of Korean Society of Menopause
Año:
2010
Tipo del documento:
Artículo
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