A case of malignant histiocytosis with various skin manifestations / 대한피부과학회지
Korean Journal of Dermatology
;
: 720-726, 1992.
Artículo
en Coreano
| WPRIM
| ID: wpr-152936
ABSTRACT
Malignant histiocytosis(MH) is a rapidly progressive and usally fatal disorder characterized clinically fever, generalized weakness, lymphadeno athy, hepatosplenomegaly accompanied by jaundice, and purpura. The frequency of skin manifestations has been repoterd about 15% of MH patients. Papules, plaques and niidules are commonly met. Histopathologically MH shows infiltrations of atypical histiocyte; with uarious maturity in many organs including skin. We present a case of a 32-year-old female with MH involving not only lymph node, liver, spleen and bone marrow but also skin with vaorious features ; erythematous papules, annular purpuric patches, subcutaneous nodules and hemomagic nodules. Immunohist,ochemically the majority of patients atypical histiocytes in lesional skin shows a-1 antitrysin positive, but lysozyme negative. It may suggest that these are poorly differentiated atypical histiocytes rather than well differentiated ones.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Púrpura
/
Piel
/
Manifestaciones Cutáneas
/
Bazo
/
Médula Ósea
/
Muramidasa
/
Sarcoma Histiocítico
/
Fiebre
/
Histiocitos
/
Ictericia
Límite:
Adulto
/
Femenino
/
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Dermatology
Año:
1992
Tipo del documento:
Artículo
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