Prostate Cancer: Added Value of Subtraction Dynamic Imaging in 3T Magnetic Resonance Imaging with a Phased-array Body Coil
Yonsei Medical Journal
; : 765-774, 2008.
Article
en En
| WPRIM
| ID: wpr-153700
Biblioteca responsable:
WPRO
ABSTRACT
PURPOSE: To determine the added value of dynamic subtraction magnetic resonance (MR) imaging for the localization of prostate cancer. MATERIALS AND METHODS: We examined 21 consecutive patients who underwent MR imaging in 3T unit with a phased-array body coil and then had radical prostatectomy. After T2-weighted fast spin-echo imaging, we performed a contrast-enhanced dynamic 3D gradient-echo imaging consisting of pre-contrast, 2 successive early-phased (first imaging was started just after the appearance of contrast material in the aortic bifurcation followed by second imaging 35 seconds after the initiation of first imaging) and one 5-minute delayed post-contrast series. Subtraction of pre-contrast images from corresponding post-contrast images of each phase was performed on the console. RESULTS: On ROC analysis, the overall accuracy (Az value) of dynamic imaging combined with subtraction imaging was higher than T2-weighted imaging (p = 0.001) or conventional dynamic imaging alone (p = 0.074) for localization of cancer foci regardless of their zonal locations. Among pathologically verified 81 lesions, the mean volume of detected lesions with the subtraction images (n = 49, 0.69cm3) was smaller than with T2-weighted images (n = 14, 1.05cm3) or conventional dynamic images (n = 43, 0.71cm(3)). CONCLUSION: For localization of small prostate cancer, additional subtraction for the dynamic imaging could be superior to both T2-weighted imaging and un-subtracted dynamic imaging.
Palabras clave
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Próstata
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Neoplasias de la Próstata
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Imagen por Resonancia Magnética
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Estudios Retrospectivos
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Sensibilidad y Especificidad
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
Límite:
Aged
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Humans
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Male
Idioma:
En
Revista:
Yonsei Medical Journal
Año:
2008
Tipo del documento:
Article