Clinical Analysis on 13 Korean Cases of Darier's Disease / 대한피부과학회지
Korean Journal of Dermatology
;
: 1070-1076, 2002.
Artículo
en Coreano
| WPRIM
| ID: wpr-154293
ABSTRACT
BACKGROUND:
Darier's disease is an autosomal dominant disoder in keratinizing process. Clinically, patients present with warty to hyperkeratotic plaques with predilection of seborrheic area.OBJECTIVES:
The purpose of this study was to analyze the clinical findings of Darier's disease in Koreans with literature review.METHODS:
Thirteen cases of Darier's disease were reviewed by retrospective study. We analyzed the patients in terms of their clinical features, such as age, sex, family background, location of present or initial lesions, severity, clinical types, and treatment or prognosis.RESULTS:
Darier's disease in Koreans was predominant in male with a sex ratio between male female of 10 3. Three patients had a family history of Darier's disease among siblings and ancestors. Young patients under 30 years old were 79% with average onset of 24 years old. Typical seborrheic type was found in 9 cases, and flexural and linear/nevoid types were 2 cases, respectively. Characteristic nail deformities were observed in 5 cases, all of them showed V-shaped nicking. Focal types responded well to retinoic acid treatment, while seborrheic type was poor to treatment.CONCLUSION:
We reviewed clinical characteristics of Darier's disease in Koreans patients. Interestingly, male-dominance of Darier's disease in Korean suggests the possibility that genetic patterns vary among countries or races in Darier's disease.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Pronóstico
/
Razón de Masculinidad
/
Anomalías Congénitas
/
Tretinoina
/
Estudios Retrospectivos
/
Hermanos
/
Grupos Raciales
/
Enfermedad de Darier
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
Límite:
Adulto
/
Femenino
/
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Korean Journal of Dermatology
Año:
2002
Tipo del documento:
Artículo
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