Your browser doesn't support javascript.
loading
Two Cases of Successful Use of Urokinase in Continuous Ambulatory Peritoneal Dialysis Patients with Relapsing Peritonitis / 대한신장학회잡지
Korean Journal of Nephrology ; : 830-835, 2004.
Artículo en Coreano | WPRIM | ID: wpr-154470
ABSTRACT
Peritonitis is a frequent and serious complication in continuous ambulatory peritoneal dialysis (CAPD) patients. Recently, due to educational promotion in general hygiene and development of laboratory technique for bacterial cultures and sensitivity test, proper use of antibiotics, the incidence of CAPD peritonitis has gradually decreased. However, CAPD peritonitis is still one of the most common causes of peritoneal dialysis failure and of removal peritoneal catheter. It has been suggested that the formation of biofilm on the inner surface of peritoneal catheter leads to relapsing peritonitis and removal of the peritoneal catheter in CAPD patients. The biofilm is a kind of protecting coat which consists of fibrin inhibiting the penetration of antibiotics. It surrounds and covers the bacteria, making them to survive from the attack of antibiotics. Therefore thrombolytic therapy, urokinase modifies the structure of biofilm, and helps the antibiotics penetrating the fibrin coat, eventually amplify the bacteriocidal effect. We experienced two cases of successful treatment with urokinase and antibiotics in CAPD peritonitis patients. The combination of thrombolytic agents and antibiotics might be one of the strategies for the treatment of CAPD patients who experienced it frequently.
Asunto(s)

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Peritonitis / Bacterias / Fibrina / Activador de Plasminógeno de Tipo Uroquinasa / Terapia Trombolítica / Higiene / Incidencia / Diálisis Peritoneal / Diálisis Peritoneal Ambulatoria Continua / Biopelículas Tipo de estudio: Estudio de incidencia / Estudio pronóstico Límite: Humanos Idioma: Coreano Revista: Korean Journal of Nephrology Año: 2004 Tipo del documento: Artículo

Similares

MEDLINE

...
LILACS

LIS

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Peritonitis / Bacterias / Fibrina / Activador de Plasminógeno de Tipo Uroquinasa / Terapia Trombolítica / Higiene / Incidencia / Diálisis Peritoneal / Diálisis Peritoneal Ambulatoria Continua / Biopelículas Tipo de estudio: Estudio de incidencia / Estudio pronóstico Límite: Humanos Idioma: Coreano Revista: Korean Journal of Nephrology Año: 2004 Tipo del documento: Artículo