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The Risk Factors for Increased Post-Voiding Residual Urine Volume after Long-Term Anticholinergic Therapy in Patients with Benign Prostatic Hyperplasia and Overactive Bladder
Korean Journal of Urology ; : 982-988, 2009.
Artículo en Coreano | WPRIM | ID: wpr-155598
ABSTRACT

PURPOSE:

Adding anticholinergics to the treatment regimen of benign prostatic hyperplasia (BPH) patients with overactive bladder (OAB) elicits concern about deterioration of obstructive symptoms and the possibility of urine retention. We evaluated the risk factors increasing post-voiding residual (PVR) volume with long-term anticholinergics therapy of over 1 year in patients with BPH and OAB. MATERIALS AND

METHODS:

We selected patients with BPH and OAB from 2005 to 2007 who were more than 40 years old, were treated with alpha-blockers, had an International Prostate Symptom Score (IPSS) of 8 or more, and had an IPSS urgency score of 2 or more for OAB. The 98 patients selected were evaluated by age, diabetes mellitus, central nervous system (CNS) disease above the brain stem, prostate volume, uroflowmetry, PVR volume, prostate-specific antigen (PSA) level, and IPSS retrospectively. We evaluated risk factors for increasing PVR volume over 50 ml and 100 ml after treatment and analyzed the risk factors both univariately and multivariately.

RESULTS:

Age, diabetes mellitus, CNS disease, PSA level, prostate volume, initial PVR volume, peak urine flow rate ( or=65 years), initial PVR (> or=50 ml), long-term therapy with anticholinergics of over 1 year, and CNS disease appear to be risk factors for increasing PVR volume over 100 ml in patients with BPH and OAB.
Asunto(s)

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Próstata / Hiperplasia Prostática / Retención en Psicología / Tronco Encefálico / Sistema Nervioso Central / Enfermedades del Sistema Nervioso Central / Análisis Multivariante / Estudios Retrospectivos / Factores de Riesgo / Antígeno Prostático Específico Tipo de estudio: Estudio de etiología / Estudio observacional / Factores de riesgo Límite: Humanos Idioma: Coreano Revista: Korean Journal of Urology Año: 2009 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Próstata / Hiperplasia Prostática / Retención en Psicología / Tronco Encefálico / Sistema Nervioso Central / Enfermedades del Sistema Nervioso Central / Análisis Multivariante / Estudios Retrospectivos / Factores de Riesgo / Antígeno Prostático Específico Tipo de estudio: Estudio de etiología / Estudio observacional / Factores de riesgo Límite: Humanos Idioma: Coreano Revista: Korean Journal of Urology Año: 2009 Tipo del documento: Artículo