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The Comparison between Early Enteral Nutrition and Total Parenteral Nutrition after Total Gastrectomy in Patients with Gastric Cancer: The Randomized Prospective Study / 대한소화기학회지
The Korean Journal of Gastroenterology ; : 407-413, 2012.
Artículo en Coreano | WPRIM | ID: wpr-155647
ABSTRACT
BACKGROUND/

AIMS:

Early enteral nutrition (EEN) has benefits in reducing infectious complication, length of stay (LOS) and preserving liver function. There are few data about the effect of EEN in the patients who had total gastrectomy. The aim of this randomized and prospective study was to evaluate the effect of EEN after total gastrectomy on nutritional status, liver function, complications and LOS, compared to total parenteral nutrition (TPN) in patients with gastric cancer.

METHODS:

Among 56 patients with gastric cancer, 36 and 20 were randomly assigned to EEN and TPN groups, and finally 17 and 16 completed EEN and TPN schedules, respectively. The nutritional parameters, liver function, LOS and abdominal symptoms were compared between 2 groups on pre-operative day and post-operative 7th day.

RESULTS:

There was no significant difference in the nutritional parameters, liver function between EEN and TPN groups. Vomiting and abdominal distention were more frequent in EEN than TPN group (2 vs. 0 cases, p=0.485; 1 vs. 0 case, p=1.000, respectively), while increased AST, ALT and total bilirubin were more common in TPN than EEN group (4 vs. 2 cases, p=0.398; 1 vs. 0 case, p=0.485, respectively without statistical significance). LOS was shorter in EEN than TPN group without statistical significance (12 vs. 13 days, p=0.289).

CONCLUSIONS:

No significant differences were found in the nutritional status parameters, liver function, complications and LOS between EEN and TPN groups on 7th day after total gastrectomy. Further large scale studies on the advantages and disadvantages of EEN after total gastrectomy are warranted.
Asunto(s)

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Cuidados Posoperatorios / Aspartato Aminotransferasas / Neoplasias Gástricas / Bilirrubina / Estudios Prospectivos / Nutrición Enteral / Nutrición Parenteral Total / Alanina Transaminasa / Gastrectomía / Tiempo de Internación Tipo de estudio: Ensayo Clínico Controlado / Estudio observacional Límite: Adulto / Anciano / Aged80 / Femenino / Humanos / Masculino Idioma: Coreano Revista: The Korean Journal of Gastroenterology Año: 2012 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Cuidados Posoperatorios / Aspartato Aminotransferasas / Neoplasias Gástricas / Bilirrubina / Estudios Prospectivos / Nutrición Enteral / Nutrición Parenteral Total / Alanina Transaminasa / Gastrectomía / Tiempo de Internación Tipo de estudio: Ensayo Clínico Controlado / Estudio observacional Límite: Adulto / Anciano / Aged80 / Femenino / Humanos / Masculino Idioma: Coreano Revista: The Korean Journal of Gastroenterology Año: 2012 Tipo del documento: Artículo