Endoscopic Treatment of an Isolated Diffuse Hyperplastic Gastric Polyposis Containing Adenocarcinoma

ABSTRACT

Gastric hyperplastic polyps constitute one of the most common types of polyp in patients undergoing an upper endoscopy, and are found with a frequency as high as 60% of all polyps. However, isolated diffuse hyperplastic gastric polyposis is seldom reported. Here, we present a case of isolated diffuse hyperplastic gastric polyposis in a 30-year-old man who was investigated for iron deficiency anemia during routine screening. Esophagogastroduodenoscopy revealed numerous polyps on the antrum of the stomach, and the polyps were removed completely by endoscopic polypectomy. An adenocarcinoma that arose from a large hyperplastic polyp was found after its removal. This case suggests that despite the rarity of isolated diffuse hyperplastic gastric polyposis, it can be managed by endoscopic treatment.