The Prognostic Value of the Preoperative Lymphocyte Count in Patients with Gastric Cancer
Journal of the Korean Gastric Cancer Association
;
: 26-30, 2009.
Artículo
en Coreano
| WPRIM
| ID: wpr-15703
ABSTRACT
PURPOSE:
The aim of this study was to evaluate the prognostic value of the peripheral blood lymphocyte count before surgery in those patients with gastric cancer. MATERIALS ANDMETHODS:
The study group was comprised of a series of 1,054 patients who underwent curative gastrectomy. The appropriate lymphocyte count cutoff value was determined. The prognostic factors were evaluated by univariate and multivariate analyses.RESULTS:
The lymphocyte count cutoff value was 1,500/ul. The patients were classified into two groups Group A had a lymphocyte count > or =1,500/ul (n=765) and Group B had a lymphocyte count <1,500/ul (n=289). There were statistically significant differences between the groups according to their age (P<0.001), the tumor stage (P=0.038) and the tumor size (P<0.001). The 5- and 10-year survival rates of Group A were 80.1% and 76.6%, respectively and those of Group B were 72.4% and 63.5%, respectively (P=0.002). When multivariate analysis was performed by the Cox proportional hazards model, the lymphocyte count was not an independent prognostic factor.CONCLUSION:
Although the prognosis of patients with a high lymphocyte count was better than that of the patients with a low lymphocyte count, our results did not support using the preoperative peripheral blood lymphocyte count as an independent prognostic factor for patients with gastric cancer.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Pronóstico
/
Neoplasias Gástricas
/
Linfocitos
/
Modelos de Riesgos Proporcionales
/
Análisis Multivariante
/
Tasa de Supervivencia
/
Recuento de Linfocitos
/
Gastrectomía
Tipo de estudio:
Estudio pronóstico
Límite:
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Gastric Cancer Association
Año:
2009
Tipo del documento:
Artículo
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