Identification of Anti-G in Pregnant Women with RhD Negative Blood: The First Case in Korea / 대한수혈학회지
Korean Journal of Blood Transfusion
;
: 304-310, 2017.
Artículo
en Coreano
| WPRIM
| ID: wpr-158036
ABSTRACT
Anti-G positivity can be misinterpreted as the presence of anti-D or -C antigen in an antibody identification test, as this antibody is known to show agglutination to D or C antigen-positive red cells. Correct identification of anti-G is important in pregnant women, as prenatal care or the need for RhIG administration can vary between anti-D and -C versus anti-G cases. We recently encountered a D-negative case with suspected anti-D and -C, which was ruled out by adsorption and elution tests, and ultimately confirmed the presence of anti-G. The pregnant woman was a 33-year-old patient with cde Rh phenotype with a previous history of spontaneous abortion, followed by administration of RhIG. The spouse's Rh phenotype was CDe. Initial antibody identification test showed 2+ positivity to C (homozygotes and heterozygotes) and trace to 1+ positivity to D. Upon additional adsorption and elution with R0r (cDe/cde) and r'r (Cde/ cde) red cells, we identified the antibody present in the patient's serum as anti-G. The patient is currently under close follow-up monitoring for anti-G titer using antibody titer testing with both CDe and CcDEe red cells. Periodic fetal cerebral Doppler examination is being carried out without evidence of fetal distress.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Fenotipo
/
Atención Prenatal
/
Aborto Espontáneo
/
Estudios de Seguimiento
/
Globulina Inmune rho(D)
/
Adsorción
/
Aglutinación
/
Mujeres Embarazadas
/
Sufrimiento Fetal
/
Corea (Geográfico)
Tipo de estudio:
Estudio diagnóstico
/
Estudio observacional
/
Estudio pronóstico
Límite:
Adulto
/
Femenino
/
Humanos
/
Embarazo
País/Región como asunto:
Asia
Idioma:
Coreano
Revista:
Korean Journal of Blood Transfusion
Año:
2017
Tipo del documento:
Artículo
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