The Diagnosis and Treatment of Autoimmune Encephalitis
Journal of Clinical Neurology
;
: 1-13, 2016.
Artículo
en Inglés
| WPRIM
| ID: wpr-158264
ABSTRACT
Autoimmune encephalitis causes subacute deficits of memory and cognition, often followed by suppressed level of consciousness or coma. A careful history and examination may show early clues to particular autoimmune causes, such as neuromyotonia, hyperekplexia, psychosis, dystonia, or the presence of particular tumors. Ancillary testing with MRI and EEG may be helpful for excluding other causes, managing seizures, and, rarely, for identifying characteristic findings. Appropriate autoantibody testing can confirm specific diagnoses, although this is often done in parallel with exclusion of infectious and other causes. Autoimmune encephalitis may be divided into several groups of diseases those with pathogenic antibodies to cell surface proteins, those with antibodies to intracellular synaptic proteins, T-cell diseases associated with antibodies to intracellular antigens, and those associated with other autoimmune disorders. Many forms of autoimmune encephalitis are paraneoplastic, and each of these conveys a distinct risk profile for various tumors. Tumor screening and, if necessary, treatment is essential to proper management. Most forms of autoimmune encephalitis respond to immune therapies, although powerful immune suppression for weeks or months may be needed in difficult cases. Autoimmune encephalitis may relapse, so follow-up care is important.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Trastornos Psicóticos
/
Recurrencia
/
Convulsiones
/
Imagen por Resonancia Magnética
/
Linfocitos T
/
Tamizaje Masivo
/
Estudios de Seguimiento
/
Síndrome de la Persona Rígida
/
Cognición
/
Coma
Tipo de estudio:
Estudio diagnóstico
/
Estudio observacional
/
Estudio pronóstico
/
Estudio de tamizaje
Idioma:
Inglés
Revista:
Journal of Clinical Neurology
Año:
2016
Tipo del documento:
Artículo
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