Sedative Effect and Cardiovascular Stability of Lidocaine during Endotracheal Intubation under Bispectral Index (BIS) Monitoring / 대한마취과학회지
Korean Journal of Anesthesiology
;
: 161-166, 2002.
Artículo
en Coreano
| WPRIM
| ID: wpr-158921
ABSTRACT
BACKGROUND:
Lidocaine's sedative effect has not been known well. The purpose of this study was to evaluate its sedative and cardiovascular effects during induction of anesthesia.METHODS:
Twenty patients were randomly allocated to group I or II, with or without lidocaine 1.5 mg/kg intravenously (IV) before induction, respectively. The BIS, blood pressure and heart rate were measured at before and 2 minutes after lidocaine IV injection, preintubation, and 1, 2, 3 and 5 minutes after tracheal intubation. The enflurane concentrations were continuously maintained at 2 volume%.RESULTS:
The BIS of group I was more decreased at 1 and 2 minutes after intubation than those of group II. The systolic blood pressures of group I were less increased at 1 and 2 minutes after intubation than those of group II. The diastolic blood pressures and heart rates of group I were not different from those of group II at each stage of the procedure.CONCLUSIONS:
Lidocaine reduced BIS and blunted the intubation-induced systolic hypertensive response. In addition it is thought that it has a sedative effect and is effective to maintain cardiovascular stability after tracheal intubation.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Presión Sanguínea
/
Enflurano
/
Frecuencia Cardíaca
/
Hipnóticos y Sedantes
/
Intubación
/
Intubación Intratraqueal
/
Anestesia
/
Lidocaína
Límite:
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Anesthesiology
Año:
2002
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS