A Case of Esophageal Involvement of Cicatrical Pemphigoid / 대한소화기내시경학회지
Korean Journal of Gastrointestinal Endoscopy
;
: 461-465, 2001.
Artículo
en Coreano
| WPRIM
| ID: wpr-159087
ABSTRACT
Cicatrical pemphigoid is regarded as a chronic, autoimmune subepithelial blistering disease of mucous membranes in which lesions often heal with scar formation. Cicatrical pemphigoid typically involves the oral and/or ocular mucosa but may affect the nasal, pharyngeal, laryngeal, esophageal, anogenital regions as well. Immunopathologic studies have shown that patients with cicatrical pemphigoid typically have autoantibodies directed against basement membrane antigens and that they demonstrate continuous deposits of immunoglobulins (IgG, A), complement components and fibrin along the basement membrane. A 69-year-old female was admitted with chief complaints of hoarseness, dyspnea, multiple painful oral ulcer and vesiculobullous skin lesion on upper trunk. During admission, dysphagia and epigastric discomfort was developed. Endoscopic examination revealed multiple erosion and ulcerative lesion with scar formation. Immunopathologic studies showed that linear deposit of IgG, A, C3 along the basement membrane zone. We report a case of cicatrical pemphigoid with esophageal involvement with brief review of literature.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Piel
/
Autoanticuerpos
/
Úlcera
/
Membrana Basal
/
Proteínas del Sistema Complemento
/
Inmunoglobulina G
/
Inmunoglobulinas
/
Fibrina
/
Trastornos de Deglución
/
Ronquera
Límite:
Anciano
/
Femenino
/
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Gastrointestinal Endoscopy
Año:
2001
Tipo del documento:
Artículo
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