COPD Patients with Exertional Desaturation Are at a Higher Risk of Rapid Decline in Lung Function
Yonsei Medical Journal
;
: 732-738, 2014.
Artículo
en Inglés
| WPRIM
| ID: wpr-159379
ABSTRACT
PURPOSE:
A recent study demonstrated that exertional desaturation is a predictor of rapid decline in lung function in patients with chronic obstructive pulmonary disease (COPD); however, the study was limited by its method used to detect exertional desaturation. The main purpose of this study was to explore whether exertional desaturation assessed using nadir oxygen saturation (SpO2) during the 6-minute walk test (6MWT) can predict rapid lung function decline in patients with COPD. MATERIALS ANDMETHODS:
A retrospective analysis was performed on 57 patients with moderate to very severe COPD who underwent the 6MWT. Exertional desaturation was defined as a nadir SpO2 of or =50 mL. Patients were divided into rapid decliner (n=26) and non-rapid decliner (n=31) groups.RESULTS:
A statistically significant difference in exertional desaturation was observed between rapid decliners and non-rapid decliners (17 vs. 8, p=0.003). No differences were found between the groups for age, smoking status, BODE index, and FEV1. Multivariate analysis showed that exertional desaturation was a significant independent predictor of rapid decline in patients with COPD (relative risk, 6.8; 95% CI, 1.8 to 25.4; p=0.004).CONCLUSION:
This study supports that exertional desaturation is a predictor of rapid lung function decline in male patients with COPD.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Pruebas de Función Respiratoria
/
Ejercicio Físico
/
Volumen Espiratorio Forzado
/
Estudios Retrospectivos
/
Enfermedad Pulmonar Obstructiva Crónica
/
Hipoxia
Tipo de estudio:
Estudio de etiología
/
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Anciano
/
Femenino
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Yonsei Medical Journal
Año:
2014
Tipo del documento:
Artículo
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