A Case of Ascites without Liver Failure in Patient with Valproic Acid Intoxication

ABSTRACT

Valproic acid (VA) has been used for treatment of various convulsive disorders. As its use has increased, many complications of VA have been reported. Complications include significantly dangerous organ failures such as liver failure, brain edema, respiratory arrest, and pancreatitis, and so on. Some clinicians have reported rare cases of ascites with liver failure and necrotizing pancreatitis in patients with VA overdose. However, no case of ascites without organ problems has been reported. A 19 year-old man who was intoxicated with VA was transferred to our hospital. He had abdominal distension with a moderate amount of ascites despite having no organ dysfunction. We will describe this rare case.