Risk Factors for Periventricular-Intraventricular Hemorrhage in Premature Infants
Journal of Korean Medical Science
;
: 418-424, 2010.
Artículo
en Inglés
| WPRIM
| ID: wpr-161037
ABSTRACT
Periventricular-intraventricular hemorrhage (PV-IVH) is a major cause of neurological disabilities in preterm newborns. This study aimed to determine the perinatal factors associated with PV-IVH. We conducted a retrospective case-control study from preterm infants born at < or =34 weeks of gestation and admitted to Neonatal Intensive Care Units of Seoul National University Children's Hospital and Seoul National University Bundang Hospital between June 2003 and December 2007. Neonates with no cranial sonographic data or infants transferred from other centers after three days of age were excluded. Of 1,044 eligible subjects, 59 infants with PV-IVH grade 2, 3, and 4 were allocated to the case group. The control group consisted of 118 infants without PV-IVH who were matched for gestational age and birth weight to each case of PV-IVH. At the multivariate logistic regression model, metabolic acidosis (odds ratio [OR] 6.94; 95% confidence interval [CI] 1.12-43.23) and use of inotropes (OR 3.70; 95% CI 1.16-11.84) were associated with an increased risk of PV-IVH. Maternal use of antenatal corticosteroids decreases the risk of PV-IVH (OR 0.36; 95% CI 0.14-0.92).
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Acidosis
/
Peso al Nacer
/
Recien Nacido Prematuro
/
Cardiotónicos
/
Estudios de Casos y Controles
/
Oportunidad Relativa
/
Hemorragia Cerebral
/
Estudios Retrospectivos
/
Factores de Riesgo
/
Edad Gestacional
Tipo de estudio:
Estudio de etiología
/
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Adulto
/
Femenino
/
Humanos
/
Masculino
/
Recién Nacido
/
Embarazo
Idioma:
Inglés
Revista:
Journal of Korean Medical Science
Año:
2010
Tipo del documento:
Artículo
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