Diffusion-Weighted MR Imaging in Biopsy-Proven Creutzfeldt-Jakob Disease
Korean Journal of Radiology
;
: 192-196, 2001.
Artículo
en Inglés
| WPRIM
| ID: wpr-161555
ABSTRACT
OBJECTIVE:
To compare conventional and diffusion-weighted MR imaging in terms of their depiction of the abnormalities occurring in Creutzfeldt-Jakob disease. MATERIALS ANDMETHODS:
We retrospectively analyzed the findings of conventional (T2-weighted and fluid-attenuated inversion recovery) and diffusion-weighted MR imaging in four patients with biopsy-proven Creutzfeldt-Jakob disease. The signal intensity of the lesion was classified by visual assessment as markedly high, slightly high, or isointense, relative to normal brain parenchyma.RESULTS:
Both conventional and diffusion-weighted MR images demonstrated bilateral high signal intensity in the basal ganglia in all four patients. Cortical lesions were observed on diffusion-weighted MR images in all four, and on fluid-attenuated inversion recovery MR images in one, but in no patient on T2-weighted images. Conventional MR images showed slightly high signal intensity in all lesions, while diffusion-weighted images showed markedly high signal intensity in most.CONCLUSION:
Diffusion-weighted MR imaging is more sensitive than its conventional counterpart in the depiction of Creutzfeldt-Jakob disease, and permits better detection of the lesion in both the cerebral cortices and basal ganglia.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Biopsia
/
Estudio Comparativo
/
Imagen por Resonancia Magnética
/
Estudios Retrospectivos
/
Síndrome de Creutzfeldt-Jakob
/
Sensibilidad y Especificidad
/
Persona de Mediana Edad
Tipo de estudio:
Estudio diagnóstico
/
Estudio observacional
Límite:
Adulto
/
Anciano
/
Femenino
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Korean Journal of Radiology
Año:
2001
Tipo del documento:
Artículo
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