Omega-3 Polyunsaturated Fatty Acids in Prevention of Mood and Anxiety Disorders
Clinical Psychopharmacology and Neuroscience
;
: 129-137, 2015.
Artículo
en Inglés
| WPRIM
| ID: wpr-162191
ABSTRACT
Psychiatric disorders in general, and major depression and anxiety disorders in particular, account for a large burden of disability, morbidity and premature mortality worldwide. Omega-3 polyunsaturated fatty acids (PUFAs) have a range of neurobiological activities in modulation of neurotransmitters, anti-inflammation, anti-oxidation and neuroplasticity, which could contribute to psychotropic effects. Here we reviewed recent research on the benefits of omega-3 PUFA supplements in prevention against major depression, bipolar disorders, interferon-alpha-induced depression patients with chronic hepatitis C viral infection, and posttraumatic stress disorder. The biological mechanisms underlying omega-3 PUFAs' psychotropic effects are proposed and reviewed. Nutrition is a modifiable environmental factor that might be important in prevention medicine, which have been applied for many years in the secondary prevention of heart disease with omega-3 PUFAs. This review extends the notion that nutrition in psychiatry is a modifiable environmental factor and calls for more researches on prospective clinical studies to justify the preventive application of omega-3 PUFAs in daily practice.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Ansiedad
/
Trastornos de Ansiedad
/
Trastornos Psicóticos
/
Trastornos por Estrés Postraumático
/
Trastorno Bipolar
/
Neurotransmisores
/
Hepatitis C Crónica
/
Depresión
/
Ácidos Grasos Insaturados
/
Prevención Secundaria
Límite:
Humanos
Idioma:
Inglés
Revista:
Clinical Psychopharmacology and Neuroscience
Año:
2015
Tipo del documento:
Artículo
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