Association of BRAF(V600E) Mutation with Poor Clinical Prognostic Factors and Ultrasonographic Findings in Cases of Papillary Thyroid Carcinoma / 대한내분비외과학회지
Korean Journal of Endocrine Surgery
; : 16-20, 2012.
Article
en Ko
| WPRIM
| ID: wpr-162460
Biblioteca responsable:
WPRO
ABSTRACT
PURPOSE: This study evaluated the association of the BRAF(V600E) mutation with known prognostic factors and ultrasonographic characteristics in cases of papillary thyroid carcinoma. METHODS: Subjects included 169 patients who received thyroidectomy at Wonju Christian Hospital under the diagnosis of papillary thyroid cancer from February 2010 to October 2011. RESULTS: Of the total patients who received thyroidectomy, there were 128 cases (75,7%) of BRAF(V600E) mutation. Neither age nor sex were associated with the BRAF(V600E) mutation. Tumor size, shape, margin, extrathyroidal extension, central node metastasis and lateral node metastasis were found not to be associated with the BRAF(V600E) mutation. Tumor calcification, echogenicity and vascularity were also not associated with the mutation. CONCLUSION: As debate remains about the association between the BRAF(V600E) mutation and clincopathologic factors and ultrasonographic characteristics in cases of papillary thyroid carcinoma, further study is needed.
Palabras clave
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Glándula Tiroides
/
Tiroidectomía
/
Neoplasias de la Tiroides
/
Diagnóstico
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Metástasis de la Neoplasia
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Humans
Idioma:
Ko
Revista:
Korean Journal of Endocrine Surgery
Año:
2012
Tipo del documento:
Article