Peroral Endoscopic Myotomy for Treatment of Achalasia: Initial Results of a Korean Study
Clinical Endoscopy
;
: 161-167, 2013.
Artículo
en Inglés
| WPRIM
| ID: wpr-162834
ABSTRACT
BACKGROUND/AIMS:
Achalasia is a rare esophageal motility disorder. Recently, a novel endoscopic technique, peroral endoscopic myotomy (POEM), was introduced as an alternative treatment for achalasia. We report the results and short term outcomes of POEM for patients with achalasia.METHODS:
POEM was performed in 13 patients with achalasia. The procedure consisted of creating a submucosal tunnel followed by endoscopic myotomy of circular muscle bundles. The mucosal entry was closed by conventional hemostatic clips. A validated clinical symptom score (Eckardt score) and high resolution manometry were used to evaluate the outcomes.RESULTS:
Both the clinical score of achalasia, as well as the resting lower esophageal sphincter (LES) pressure, were significantly reduced after POEM. Mean posttreatment Eckardt score was 0.4+/-0.7, compared to 6.4+/-1.9 prior to the treatment (p=0.001). The mean pretreatment and posttreatment LES pressure was 30.3 and 15.3 mm Hg, respectively (p=0.007). Following POEM, symptomatic relief from dysphagia without reflux symptoms was observed in all patients (13/13). No serious complications related to POEM were encountered.CONCLUSIONS:
Based upon our initial experience, the authors believe that POEM is a feasible, safe, and effective treatment and may possibly substitute established treatments of refractory achalasia.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Trastornos de la Motilidad Esofágica
/
Trastornos de Deglución
/
Acalasia del Esófago
/
Esfínter Esofágico Inferior
/
Manometría
/
Músculos
Límite:
Humanos
Idioma:
Inglés
Revista:
Clinical Endoscopy
Año:
2013
Tipo del documento:
Artículo
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