A Case of Osmotic Demyelination Presenting with Severe Hypernatremia
Electrolytes & Blood Pressure
;
: 30-36, 2015.
Artículo
en Inglés
| WPRIM
| ID: wpr-16300
ABSTRACT
Osmotic demyelination syndrome is a demyelinating disorder associated with rapid correction of hyponatremia. But, it rarely occurs in acute hypernatremia, and it leads to permanent neurologic symptoms and is associated with high mortality. A 44-year-old woman treated with alternative medicine was admitted with a history of drowsy mental status. Severe hypernatremia (197mEq/L) with hyperosmolality (415mOsm/kgH2O) was evident initially and magnetic resonance imaging revealed a high signal intensity lesion in the pons, consistent with central pontine myelinolysis. She was treated with 0.45% saline and 5% dextrose water and intravenous corticosteroids. Serum sodium normalized and her clinical course gradually improved. Brain lesion of myelinolysis also improved in a follow-up imaging study. This is the first report of a successful treatment of hypernatremia caused by iatrogenic salt intake, and it confirms the importance of adequate fluid supplementation in severe hypernatremia.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Sodio
/
Encéfalo
/
Terapias Complementarias
/
Puente
/
Imagen por Resonancia Magnética
/
Agua
/
Estudios de Seguimiento
/
Mortalidad
/
Enfermedades Desmielinizantes
/
Corticoesteroides
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
Límite:
Adulto
/
Femenino
/
Humanos
Idioma:
Inglés
Revista:
Electrolytes & Blood Pressure
Año:
2015
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS