Angiogenic Inhibitor Induced Complicated Reflux Esophagitis / 이화의대지
The Ewha Medical Journal
;
: 58-61, 2013.
Artículo
en Inglés
| WPRIM
| ID: wpr-165467
ABSTRACT
Sunitinib an inhibitor of the vascular endothelial growth factor receptor, is highly effective against renal cell carcinoma and is now widely used in patients with metastatic disease. Gastroesophageal reflux disease (GERD) is rarely reported as a side effect of sunitinib. We report two cases of GERD with upper gastrointestinal bleeding related to sunitinib administration. Both cases responded well to conservative management. Microscopic findings in both cases showed cellular atypia such as hyperchromasia, increases in nuclear size, and multinucleation. The cellular atypia of the squamous mucosa appears to be associated with reparative processes.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Pirroles
/
Carcinoma de Células Renales
/
Esofagitis Péptica
/
Reflujo Gastroesofágico
/
Receptores de Factores de Crecimiento Endotelial Vascular
/
Hemorragia
/
Indoles
/
Membrana Mucosa
Límite:
Humanos
Idioma:
Inglés
Revista:
The Ewha Medical Journal
Año:
2013
Tipo del documento:
Artículo
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