A Case of Multiple Tuberculosis Associated with Infliximab Therapy in Crohn's Disease / 대한내과학회지
Korean Journal of Medicine
;
: 337-341, 2012.
Artículo
en Coreano
| WPRIM
| ID: wpr-165635
ABSTRACT
Infliximab, a tumor necrosis factor-alpha (TNF-alpha) inhibitor, has been approved for the treatment of a variety of inflammatory illnesses, including Crohn's disease. However, infliximab can increase the risk of reactivation of latent tuberculosis (Tbc) infection by affecting host immune responses. Therefore, a screening test should be performed before the initiation of infliximab therapy, and patients with evidence of latent infection should be treated with prophylactic anti-Tbc therapy. Here, we report a case of multifocal disseminated tuberculosis after treatment with infliximab in a patient diagnosed with Crohn's disease who had no past history of Tbc and showed a negative screening test.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Tuberculosis
/
Enfermedad de Crohn
/
Tamizaje Masivo
/
Factor de Necrosis Tumoral alfa
/
Tuberculosis Latente
/
Infliximab
/
Anticuerpos Monoclonales
Tipo de estudio:
Estudio pronóstico
/
Estudio de tamizaje
Límite:
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Medicine
Año:
2012
Tipo del documento:
Artículo
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