Small Bowel Infarction by Mesenteric Venous Thrombosis due to Methylenetetrahydrofolate Reductase Gene Mutation
Soonchunhyang Medical Science
;
: 112-115, 2014.
Artículo
en Inglés
| WPRIM
| ID: wpr-165839
ABSTRACT
Acute mesenteric venous thrombosis (MVT) is an uncommon form of intestinal ischemia with high mortality and usually occurs in the setting of preexisting comorbidities including thrombophilia and abdominal inflammatory conditions. Hyperhomocysteinemia has been known to be a risk factor for thromboembolism, often located on an unusual site. Considering that homocysteine metabolism is determined genetically to a high degree, a mutant of methylenetetrahydrofolate reductase (MTHFR) C677T causes hyperhomocysteinemia, leading to thrombophilia. Until now, there have been few reports of MVT associated with MTHFR gene mutation. We, herein, report a case of small bowel infarction associated with MVT by MTHFR gene mutation in an adult without any other risk factors of thrombophilia.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Tromboembolia
/
Trombosis
/
Comorbilidad
/
Factores de Riesgo
/
Mortalidad
/
Trombofilia
/
Trombosis de la Vena
/
Hiperhomocisteinemia
/
Metilenotetrahidrofolato Reductasa (NADPH2)
/
Homocisteína
Tipo de estudio:
Estudio de etiología
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Adulto
/
Humanos
Idioma:
Inglés
Revista:
Soonchunhyang Medical Science
Año:
2014
Tipo del documento:
Artículo
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