New Variant of O02 Allele Found in the Family of Cis-AB: Report of Three Cases in a Family / 대한수혈학회지
Korean Journal of Blood Transfusion
;
: 148-153, 2010.
Artículo
en Coreano
| WPRIM
| ID: wpr-165959
ABSTRACT
In preoperative ABO typing, we observed an ABO discrepancy in a 61 year-old patient with A2B3 phenotype. Standard serologic tests for the ABO blood group phenotypes and ABO gene direct sequencing for the exons 6 and 7 were done as part of the patient's family study. We found that the patient's genotype was identical to cis-AB01/O02, except for a 703 G>A polymorphism at exon 7. An allele-separation by cloning and subsequent sequencing of the heterozygote was carried out. We identified a novel O02 variant allele characterized by a 703 G>A polymorphism in the patient and in her 2 daughters.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Fenotipo
/
Pruebas Serológicas
/
Núcleo Familiar
/
Exones
/
Células Clonales
/
Clonación de Organismos
/
Alelos
/
Genotipo
/
Heterocigoto
Tipo de estudio:
Estudio diagnóstico
Límite:
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Blood Transfusion
Año:
2010
Tipo del documento:
Artículo
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