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Management for the Children with Otitis Media with Effusion in the Tertiary Hospital
Clinical and Experimental Otorhinolaryngology ; : 201-205, 2008.
Artículo en Inglés | WPRIM | ID: wpr-167132
ABSTRACT

OBJECTIVES:

Recently, new evidence-based recommendations have been introduced for diagnosing and managing otitis media with effusion (OME) in children. However, there are some difficulties to follow the general guidelines in the tertiary hospitals. The purpose is to evaluate the efficiency of antibiotics or antihistamines for treatment of children with OME in the tertiary hospital with a randomized prospective clinical study.

METHODS:

Eighty-four children with OME who had been diagnosed in the tertiary hospital were randomized to receive 5 different medications for 2 weeks. We prescribed antibiotics (amoxicillin-clavulanate syrup) in Group I (n=16), antibiotics/steroids (prednisolone) in Group II (n=18), antibiotics/antihistamines (ebastine) in Group III (n=15), antibiotics/steroids/antihistamines in Group IV (n=17), and mucolytics (ivy leaf extract) in Group V (n=17) for control. We followed-up children every 2 weeks and evaluated the state of OME at 3 months.

RESULTS:

Thirty six (42.9%) of 84 children were resolved within average 6.9 weeks after the treatments. Thirty-six (42.9%) were treated with ventilation tube insertion and 12 patients (14.3%) were observed. There was no difference in the resolution rates of OME among the five different protocols (P>0.05). There was no difference in the resolution rates among groups who used steroids, antihistamines, steroids and antihistamines, or other medications to manage 42 children with allergies (P>0.05).

CONCLUSION:

In the tertiary hospital, the cure rate of children with OME was not as high as well-known, and antibiotics or anti-allergic medications were not more effective than control. We may, therefore, need any other guidelines which are different from the previous evidence-based recommendations, including early operation in the tertiary hospitals.
Asunto(s)

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Otitis / Otitis Media / Esteroides / Ventilación / Otitis Media con Derrame / Estudios Prospectivos / Expectorantes / Centros de Atención Terciaria / Antagonistas de los Receptores Histamínicos / Hipersensibilidad Tipo de estudio: Ensayo Clínico Controlado / Guía de Práctica Clínica / Estudio observacional Límite: Niño / Humanos Idioma: Inglés Revista: Clinical and Experimental Otorhinolaryngology Año: 2008 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Otitis / Otitis Media / Esteroides / Ventilación / Otitis Media con Derrame / Estudios Prospectivos / Expectorantes / Centros de Atención Terciaria / Antagonistas de los Receptores Histamínicos / Hipersensibilidad Tipo de estudio: Ensayo Clínico Controlado / Guía de Práctica Clínica / Estudio observacional Límite: Niño / Humanos Idioma: Inglés Revista: Clinical and Experimental Otorhinolaryngology Año: 2008 Tipo del documento: Artículo