Diagnosis and Neurological View of Sarcopenia

ABSTRACT

Sarcopenia (Greek ‘sarx’ or flesh+‘penia’ or loss) originally is proposed as the term to describe age-related decrease of muscle mass. These days, sarcopenia is defined as a syndrome characterized by progressive loss of skeletal muscle mass and strength with a risk of adverse outcomes such as poor quality of life, physical disability, and death. In the recent decade, there are a few of consensus; European, international, and Asian consensus panels have published definitions. Additionally, measurement techniques that can be used for research and clinical practice settings according to their suitability are suggested. Many studies are reported about the association with sarcopenia and neurologic diseases, however, the results are heterogenous due to lack of sufficient studies. Some pharmacologic and non-pharmacologic methods are suggested as the intervention of sarcopenia, although there are not enough studies, yet. In this review, we summarize current understanding of the diagnostic sarcopenia and neurological point of view of sarcopenia.