A Case of Mixed Fungemia with Cryptococcus laurentii and Candida zeylanoides / 대한임상병리학회지
Korean Journal of Clinical Pathology
;
: 282-286, 2001.
Artículo
en Coreano
| WPRIM
| ID: wpr-168880
ABSTRACT
Cryptococcus laurentii is one of several non-neoformans cryptococci that have rarely been associated with human infection. Candida zeylanoides, an unusual Candida species, is also infrequently reported as a human pathogen. We report a case of mixed fungemia with C. laurentii and C. zeylanoides in a 12-year-old girl. The patient with acute myelogenous leukemia was receiving intensive remission induction chemotherapy through a central venous catheter (CVC) and was severely neutropenic. She had been treated with oral fluconazole prophylaxis since admission. C. laurentii and C. zeylanoides were simultaneously isolated from the peripheral blood cultures collected on days 29 and 31 of her hospital stay. The culture of the removed catheter tip grew >15 CFU of both C. laurentii and C. zeylanoides. In vitro susceptibility testing of the strains showed that the MIC of fluconazole for C. laurentii and C. zeylanoides were 8 microgram/mL and 4 microgram/mL, respectively. The patient was successfully treated by CVC removal and by treatment with amphotericin B intravenously. To our knowledge, this represents the first report of C. laurentii and C. zeylanoides fungemia in Korea.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Inducción de Remisión
/
Candida
/
Leucemia Mieloide Aguda
/
Fluconazol
/
Anfotericina B
/
Fungemia
/
Cryptococcus
/
Quimioterapia
/
Catéteres
/
Catéteres Venosos Centrales
Límite:
Niño
/
Femenino
/
Humanos
País/Región como asunto:
Asia
Idioma:
Coreano
Revista:
Korean Journal of Clinical Pathology
Año:
2001
Tipo del documento:
Artículo
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