A case of valproic acid-induced hyperammonemic encephalopathy with normal liver function / 대한내과학회지
Korean Journal of Medicine
;
: 680-684, 2008.
Artículo
en Coreano
| WPRIM
| ID: wpr-169544
ABSTRACT
Valproic acid is an effective anticonvulsant used in neurology and psychiatry. Valproic acid-induced hyperammonemic encephalopathy is an unusual complication characterized by a decreasing level of consciousness, the development of progressive confusional states and, sometimes, a coexisting increase in the frequency of seizures after the onset of valproic acid treatment. It can lead to death, but can be reversed if a swift diagnosis is made. We report the case of a 58-year-old woman with an intracerebral hemorrhage and normal liver function who presented with valproic acid-induced hyperammonemic encephalopathy. After valproic acid treatment, she developed encephalopathy and became comatose, with seizures and a markedly elevated serum ammonia level. Her neurologic manifestations and hyperammonemia improved after discontinuing the valproic acid.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Convulsiones
/
Hemorragia Cerebral
/
Ácido Valproico
/
Coma
/
Estado de Conciencia
/
Hiperamonemia
/
Amoníaco
/
Hígado
/
Manifestaciones Neurológicas
/
Neurología
Límite:
Femenino
/
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Medicine
Año:
2008
Tipo del documento:
Artículo
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