Changes in Serum Adenosine Deaminase Activity during Normal Pregnancy
Journal of Korean Medical Science
;
: 718-721, 2007.
Artículo
en Inglés
| WPRIM
| ID: wpr-169943
ABSTRACT
Adenosine deaminase (ADA), an enzyme essential for the differentiation of lymphoid cells, has been used for monitoring diseases with altered immunity. The purpose of this study was to investigate the changes in serum ADA activity throughout normal pregnancy. We measured the catalytic values of serum ADA from 202 normal pregnant women using a commercial kit. Subjects were divided into four groups according to the gestational age in weeks (Gwks) (Group I 5-9 Gwks [n=58]; Group II 15-20 Gwks [n= 63]; Group III 24-30 Gwks [n=34]; Group IV 30-39 Gwks [n=47]). The serum ADA levels for the Groups I, II, III, and IV were as follows 20.1+/-6.9 IU/L, 20.0+/-7.6 IU/L, 37.9+/-19.9 IU/L, and 24.5+/-8.6 IU/L, respectively. The serum ADA activity of group III was significantly higher than the other groups (p<0.05). However, there was no significant correlation between the Gwks and the serum ADA activity. Furthermore, other parameters, such as maternal age (p=0.29), gestational age at delivery (p=0.07), delivery mode (p=0.39), and birth weight (p=0.59) had no correlation with ADA activity. Reference values of serum ADA in normal pregnancy may provide important database for making clinical decisions in pregnancies complicated by conditions where cellular immunity has been altered.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Especificidad por Sustrato
/
Peso al Nacer
/
Modelos Logísticos
/
Adenosina
/
Adenosina Desaminasa
/
Análisis de Varianza
/
Edad Gestacional
/
Edad Materna
/
Inosina
Tipo de estudio:
Estudio pronóstico
/
Factores de riesgo
Límite:
Adulto
/
Femenino
/
Humanos
/
Recién Nacido
/
Embarazo
Idioma:
Inglés
Revista:
Journal of Korean Medical Science
Año:
2007
Tipo del documento:
Artículo
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