Continuous infusion of two doses of remifentanil immediately after laparoscopic-assisted vaginal hysterectomy / 대한마취과학회지
Korean Journal of Anesthesiology
;
: 537-541, 2010.
Artículo
en Inglés
| WPRIM
| ID: wpr-170125
ABSTRACT
BACKGROUND:
We evaluated the effect and safety of the immediate postoperative continuous infusion of remifentanil at two doses in patients undergoing laparoscopic-assisted vaginal hysterectomy (LAVH) with alfentanil-based patient-controlled analgesia (PCA).METHODS:
The study enrolled 50 ASA physical status 1 or 2 patients scheduled to undergo LAVH. Anesthesia was maintained with sevoflurane-remifentanil-air. At the last skin suture, the sevoflurane was discontinued, and patients were randomized to receive remifentanil 0.05 microgram/kg/min (group I) or 0.1 microgram/kg/min (group II). PCA was started at the time of eye opening and response to a verbal command. In the recovery room, we monitored the mean arterial blood pressure (MAP), heart rate (HR), respiratory rate (RR), SpO2, and bispectral index (BIS) at 5-minute intervals. Thirty minutes after starting PCA, the remifentanil was discontinued. Pain was assessed using a visual analog scale (0 = no pain; 100 = the worst possible pain) at 0, 5, 10, and 30 minutes after stopping the remifentanil infusion.RESULTS:
The eye opening time, BIS, MAP, and HR did not differ significantly between the two groups, and pain scores were similar between the two groups. Respiratory depression (SpO2 < 90% or RR < 8/min) did not occur in group I but did occur in three patients in group II.CONCLUSIONS:
Continuous remifentanil infusion (0.05 microgram/kg/min) immediately postoperatively with alfentanil-based PCA had a similar effect as a 0.1 microgram/kg/min infusion with respect to pain control without side effects. However, special attention must be given to respiratory depression.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Piperidinas
/
Sala de Recuperación
/
Insuficiencia Respiratoria
/
Piel
/
Suturas
/
Anafilaxis Cutánea Pasiva
/
Analgesia Controlada por el Paciente
/
Ojo
/
Frecuencia Respiratoria
/
Presión Arterial
Tipo de estudio:
Ensayo Clínico Controlado
Límite:
Femenino
/
Humanos
Idioma:
Inglés
Revista:
Korean Journal of Anesthesiology
Año:
2010
Tipo del documento:
Artículo
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