Metallo-beta-Lactamase-Producing Pseudomonas spp. in Korea: High Prevalence of Isolates with VIM-2 Type and Emergence of Isolates with IMP-1 Type
Yonsei Medical Journal
;
: 335-339, 2009.
Artículo
en Inglés
| WPRIM
| ID: wpr-170638
ABSTRACT
PURPOSE:
Two Korean nationwide studies showed that metallo-beta-lactamases (MBLs)-producing-Pseudomonas spp. are not rare. The aim of this study was to assess the trends of MBL-producing isolates among imipenem-resistant isolates of Pseudomonas spp. MATERIALS ANDMETHODS:
Imipenem-resistant clinical isolates were collected from 23 hospitals and one commercial laboratory participating in the KONSAR program in 2005. Polymerase chain reaction (PCR) was used to detect MBL genes.RESULTS:
Alleles of MBL genes were detected in 10.8% of 415 Pseudomonas aeruginosa and 66.7% of 12 P. putida isolates from 18 of 24 hospitals/laboratory. Among the 14 IMP-1-like and 39 VIM-2-like MBLs, emergence of IMP-6 was detected for the first time.CONCLUSION:
Prevalence of MBL-producing P. aeruginosa has not significantly increased, but IMP-6 emerged in P. aeruginosa.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Pseudomonas aeruginosa
/
Infecciones por Pseudomonas
/
Beta-Lactamasas
/
Imipenem
/
Reacción en Cadena de la Polimerasa
/
Electroforesis en Gel de Campo Pulsado
/
Corea (Geográfico)
/
Antibacterianos
Tipo de estudio:
Estudio de prevalencia
Límite:
Humanos
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Yonsei Medical Journal
Año:
2009
Tipo del documento:
Artículo
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