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Herpes Simplex Virus Duodenitis Accompanying Crohn's Disease / 대한소화기학회지
The Korean Journal of Gastroenterology ; : 292-295, 2013.
Artículo en Inglés | WPRIM | ID: wpr-171343
ABSTRACT
Herpes simplex virus (HSV) is a recognized cause of gastrointestinal infection in immunodeficient patients. Although a few cases of HSV gastritis and colitis in immunocompromised patients have been reported, there are no reports of HSV duodenitis in patients with Crohn's disease (CD). A 74-year-old female was admitted with general weakness and refractory epigastric pain. She had been diagnosed with CD three years ago. Esophagogastroduodenoscopy (EGD) revealed diffuse edematous and whitish mucosa with multiple erosions in the duodenum. Considering the possibility of viral co-infection, cytomegalovirus (CMV) immunohistochemical staining, PCR, and cultures of duodenal biopsies were performed, all of which were negative with the exception of the isolation of HSV in culture. After administration of intravenous acyclovir for 1 week, follow-up EGD showed almost complete resolution of the lesions and the patient's symptoms improved. In CD patients with refractory gastrointestinal symptoms, HSV, as well as CMV, should be considered as a possible cause of infection, so that the diagnosis of viral infection is not delayed and the appropriate antiviral treatment can be initiated.
Asunto(s)

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Antivirales / Aciclovir / ADN Viral / Enfermedad de Crohn / Reacción en Cadena de la Polimerasa / Endoscopía del Sistema Digestivo / Simplexvirus / Duodenitis / Herpes Simple / Mucosa Intestinal Límite: Anciano / Femenino / Humanos Idioma: Inglés Revista: The Korean Journal of Gastroenterology Año: 2013 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Antivirales / Aciclovir / ADN Viral / Enfermedad de Crohn / Reacción en Cadena de la Polimerasa / Endoscopía del Sistema Digestivo / Simplexvirus / Duodenitis / Herpes Simple / Mucosa Intestinal Límite: Anciano / Femenino / Humanos Idioma: Inglés Revista: The Korean Journal of Gastroenterology Año: 2013 Tipo del documento: Artículo