Molecular Neuroimaging in Posttraumatic Stress Disorder
Experimental Neurobiology
;
: 277-295, 2016.
Artículo
en Inglés
| WPRIM
| ID: wpr-172191
ABSTRACT
Over the past decade, an increasing number of neuroimaging studies have provided insight into the neurobiological mechanisms of posttraumatic stress disorder (PSTD). In particular, molecular neuroimaging techniques have been employed in examining metabolic and neurochemical processes in PTSD. This article reviews molecular neuroimaging studies in PTSD and focuses on findings using three imaging modalities including positron emission tomography (PET), single photon emission computed tomography (SPECT), and magnetic resonance spectroscopy (MRS). Although there were some inconsistences in the findings, patients with PTSD showed altered cerebral metabolism and perfusion, receptor bindings, and metabolite profiles in the limbic regions, medial prefrontal cortex, and temporal cortex. Studies that have investigated brain correlates of treatment response are also reviewed. Lastly, the limitations of the molecular neuroimaging studies and potential future research directions are discussed.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Perfusión
/
Trastornos por Estrés Postraumático
/
Lóbulo Temporal
/
Encéfalo
/
Espectroscopía de Resonancia Magnética
/
Tomografía Computarizada de Emisión de Fotón Único
/
Corteza Prefrontal
/
Tomografía de Emisión de Positrones
/
Neuroimagen
/
Metabolismo
Límite:
Humanos
Idioma:
Inglés
Revista:
Experimental Neurobiology
Año:
2016
Tipo del documento:
Artículo
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