Investigation of Splicing Quantitative Trait Loci in Arabidopsis thaliana
Genomics & Informatics
;
: 211-215, 2016.
Artículo
en Inglés
| WPRIM
| ID: wpr-172198
ABSTRACT
The alteration of alternative splicing patterns has an effect on the quantification of functional proteins, leading to phenotype variation. The splicing quantitative trait locus (sQTL) is one of the main genetic elements affecting splicing patterns. Here, we report the results of genome-wide sQTLs across 141 strains of Arabidopsis thaliana with publicly available next generation sequencing datasets. As a result, we found 1,694 candidate sQTLs in Arabidopsis thaliana at a false discovery rate of 0.01. Furthermore, among the candidate sQTLs, we found 25 sQTLs that overlapped with the list of previously examined trait-associated single nucleotide polymorphisms (SNPs). In summary, this sQTL analysis provides new insight into genetic elements affecting alternative splicing patterns in Arabidopsis thaliana and the mechanism of previously reported trait-associated SNPs.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Fenotipo
/
Arabidopsis
/
Empalme Alternativo
/
Polimorfismo de Nucleótido Simple
/
Sitios de Carácter Cuantitativo
/
Conjunto de Datos
Idioma:
Inglés
Revista:
Genomics & Informatics
Año:
2016
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS