The Clinical Study on Aluminum Levels in Patients Undergoing Hemodialysis / 대한신장학회지
Korean Journal of Nephrology
;
: 435-439, 2007.
Artículo
en Coreano
| WPRIM
| ID: wpr-173285
ABSTRACT
PURPOSE:
This study was performed to evaluate the aluminum level in hemodialysis patients and to find a correlation between aluminum level and bone specific alkaline phosphatase level.METHODS:
Eighty five randomly selected patients with end-stage renal disease, undergoing maintenance hemodialysis treatment over 1 year were studied. Serum aluminum and bone specific alkaline phosphatase concentration were measured. Low dose desferrioxamine test (5 mg/kg) was done.RESULTS:
The serum aluminum concentration before and after low dose desferrioxamine test were 4.21+/-2.13 microgram/L and 8.89+/-4.48 microgram/L (p<0.01) respectively. Bone-specific alkaline phosphates and parathyroid hormone concentration were 39.08+/-39.90 mg/dL and 98.27+/-112.92 pg/mL. The aluminum level after desferrioxamine test was correlated with duration of hemodialysis (r=0.238, p=0.03). Aluminum level was not correlated with bone specific alkaline phosphatase level.CONCLUSION:
Aluminum level was lower than that of previous studies. Aluminum level was not increased in patients with low bone specific alkaline phosphatase. Thus, it seems that serum aluminum level is not a major problem in hemodialysis patients with lower turnover bone disease. However, confirm diagnosis of aluminum related bone disease in hemodialysis patients needs combined study of bone histology with a large number of cases.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Hormona Paratiroidea
/
Fosfatos
/
Trastorno Mineral y Óseo Asociado a la Enfermedad Renal Crónica
/
Enfermedades Óseas
/
Diálisis Renal
/
Deferoxamina
/
Diagnóstico
/
Fosfatasa Alcalina
/
Aluminio
/
Fallo Renal Crónico
Tipo de estudio:
Estudio diagnóstico
Límite:
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Nephrology
Año:
2007
Tipo del documento:
Artículo
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